What Is Ethylene Oxide (EO) Sterilization?
Ethylene oxide (EO) sterilization is a widely used chemical sterilization method that eliminates microorganisms by reacting EO gas with their vital cellular components. It is especially suitable for materials and instruments that are sensitive to heat or moisture. 1. How EO Sterilization Works Mechanism of Action:Ethylene oxide achieves sterilization by alkylating functional groups of proteins […]
Understanding Ethylene Oxide (EO) Sterilization: History, Mechanism, Process, and Safety
Historical Background of Ethylene Oxide (EO) Year Milestone 1859 Ethylene oxide was first discovered by Charles Adolphe Wurtz. 1920s–1940s Widely used as a fumigant and pesticide in the food industry (e.g. spices). 1940s–1950s EO was experimentally proven effective for sterilizing medical/lab equipment. 1950s–1960s First commercial EO sterilizers developed for routine hospital use. Present EO is […]
What are the advantages and disadvantages of ethylene oxide for sterilization?

Ethylene oxide (EO) is a broad-spectrum sterilant that can kill various microorganisms such as bacterial propagules, fungal spores, viruses and spores. It is the second generation of chemical disinfectants after formaldehyde, and it is also the only most reliable chemical gas sterilant recognized by the world so far. In this issue, Yongling Medical introduces the […]